Original bug report:
    https://bugs.gentoo.org/641216

On ia64 glibc's ./configure (false) detects IFUNC support on gcc built as --enable-default-pie. This manifests as crashes when calling IFUNC-resolved functions from librt:

    $ cat a.c
    #include <time.h>
    #include <stdio.h>

    int main() {
        struct timespec t;
        int r = clock_getres(CLOCK_REALTIME, &t);
        printf ("r=%i; tv_sec=%llu, tv_nsec=%llu\n", r, (unsigned long long)t.tv_sec, (unsigned long long)t.tv_nsec);
    }

    $ gcc -Wall a.c -o a
    $ ./a
    r=0; tv_sec=0, tv_nsec=4000000
    # ok

    $ gcc -Wall a.c -o a -lrt
    $ ./a
    SIGSEGV (core dumped)
    # crash

    $ LD_BIND_NOW=1 ./a
    r=339656; tv_sec=0, tv_nsec=0
    # garbage data


Relevant log snippet from config.log:

  configure:3948: checking for assembler and linker STT_GNU_IFUNC support

  Relocation section '.rela.dyn' at offset 0x1b0 contains 1 entries:
    Offset          Info           Type           Sym. Value    Sym. Name + Addend
0000000102e8  00000000006f R_IA64_REL64LSB                      1d0
  configure:3979: result: yes

It should be an _IRELATIVE relocation to declare ifunc support. This is unrelated relocation.

Instead glibc checks for any relocations and gets tricked by unrelated relocation:
    https://sourceware.org/git/?p=glibc.git;a=blob;f=configure.ac;h=ca1282a6b3f8c5369c133a47f5c8239c3f2d32b5;hb=HEAD#l597

Building glibc with libc_cv_ld_gnu_indirect_function=no restores librt.so calls.

Basically this test is too weak to detect ifunc support:

 619   LC_ALL=C $READELF -r conftest | grep 'no relocations' >/dev/null || {
 620     libc_cv_ld_gnu_indirect_function=yes
 621   }

One of the solutions would be to build final binary with -no-pie / -nopie (depends on gcc version).
Another would be to grep specifically for R_.+_IRELATIVE (repends on reloaction names).

List of likely unaffected targets (given new enough binutils):
  #define R_386_IRELATIVE    42
  #define R_SPARC_IRELATIVE       249
  #define R_PPC_IRELATIVE         248
  #define R_PPC64_IRELATIVE       248
  #define R_AARCH64_P32_IRELATIVE
  #define R_AARCH64_IRELATIVE     1032
  #define R_ARM_IRELATIVE         160
  #define R_390_IRELATIVE         61
  #define R_X86_64_IRELATIVE      37

List of likely affected targets (don't know how many of those are linux/pie capable):
    #define R_68K_
    #define R_MIPS_
    #define R_PARISC_
    #define R_ALPHA_
    #define R_IA64_
    #define R_SH_
    #define R_CRIS_
    #define R_MN10300_
    #define R_M32R_
    #define R_MICROBLAZE_
    #define R_MICROBLAZE_64_
    #define R_NIOS2_
    #define R_TILEPRO_
    #define R_TILEGX_
    #define R_BPF_
    #define R_METAG_