autoconf configure scripts and cross-compiling

[Gareth Boden <Gareth dot Boden at human-it dot co dot uk>]

What's the 'right' way to handle configure scripts generated by autoconf
when cross-compiling? Is it simply a case
of taking the entire target machines' set of libraries and headers and
putting them in a folder on the host machine?
If so, how do you inform configure that you want the stuff built to go
in the normal place (e.g. /usr) but whilst you're building all, all the
contents that would be in /usr (libraries, includes, etc) can be found
in /usr/<target>?

Some hints would be handy, thanks.

Gareth
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